Purpose Population Dosage
As an anesthetic before surgery Adults 100–150 mg given before surgery. Dose can be repeated after 1 minute depending on patient response. Max dose 500 mg.
Children 2–7 mg/kgBW given before surgery. Dose can be repeated after 1 minute from the first injection. Max dose 7 mg/kgBW.
Treating status epilepticus Adults 75–125 mg (equivalent to 3–5 ml of 2.5% thiopental solution), given as soon as seizures appear.
Children 5 mg/kgBW given via slow IV injection.
Reducing intracranial pressure Adults 1.5–3.5 mg/kgBW.
Children ≥3 months 5-10 mg/kgBW directly injected into blood vessels, followed by an infusion of 1–4 mg/kgBW per hour.